Over two weeks of protests mark the most serious challenge in years to Iran's theocratic leadership in their scale and nature but it is too early to predict the immediate demise of the Islamic republic, analysts say.

US President Donald Trump said Sunday that Iran's leadership had called him seeking "to negotiate" after he repeatedly threatened to intervene militarily if Tehran killed protesters.

The US and Israel are meddling in the unrest shaking Iran, the country’s president, Masoud Pezeshkian, said in a televised interview on Sunday.

Iran's Supreme Leader Ayatollah Ali Khamenei has called anti-government protesters "troublemakers" who are trying "to please the president of the US".

Iranians took to the streets in new protests Friday to press the biggest movement against the Islamic republic in more than three years, as authorities sustained an internet blackout as part of a crackdown that has left dozens dead.

A nationwide internet blackout was reported in Iran on Thursday, global monitoring group NetBlocks said. Protests have been erupting across the country since late December, prompted by hyperinflation and an enduring economic crisis in the sanctioned Islamic republic.

President Donald Trump said Friday that the United States is "locked and loaded" to respond if Iran kills protesters, after cost-of-living demonstrations in the country turned deadly.

Iran has put to death a man accused of spying for Israel, the latest execution since a 12-day June war between the archenemies, the judiciary's press agency announced Saturday.

Iran’s foreign ministry called a resolution by the U.N. atomic watchdog’s board of governors “anti-Iranian” and threatened unspecified retaliatory actions, state media reported on Friday.

Iran’s supreme leader said the current situation with the United States was “unsolvable” and that Tehran would never bow to pressure to obey Washington, amid a standoff with Western powers over its nuclear program, state media reported on Sunday.

Iran said Tuesday it had not interfered in negotiations aimed at securing a ceasefire in Gaza, after US President Donald Trump claimed Tehran had issued "orders" to Palestinian group Hamas.

US strikes on Iran’s nuclear facilities were far less destructive than expected, according to intercepted communications between senior Iranian officials published by the Washington Post.