Scientists have discovered six previously unknown coronaviruses in bats as per a new research published, this week, in the scientific journal, ZooKeys. Research is part of project, “PREDICT” that investigates future challenges facing mankind; this initiative was being supported by the United States Agency for International Development (USAIDS).
ZooKeys research refers to Bats in Myanmar
The bats under study were in regions of Myanmar (previously called Burma) where humans come into close contact with wildlife as a result of agriculture, deforestation, and other ecological disruption. Scientists have identified six new coronaviruses.
Wild bats are generally beneficial for people living in many areas around the world. They pollinate crops, control pest insects, and produce excretion called guano, (bat poop: guano) which farmers collect from caves to use as fertiliser. Many experts think that these mammals were the original hosts of several viruses that pose a significant threat to human health.
These viruses include the coronaviruses that caused the outbreak of severe acute respiratory syndrome (SARS) in 2002-2003, Middle East respiratory syndrome (MERS) in 2012, and, most recently, the global pandemic of COVID-19 that began in Wuhan, China, in December 2019.
Four new species of African leaf-nosed bats have been discovered, and they're related to the horseshoe bats that have become known as the host for novel coronavirus. https://t.co/BxVel8gsz0
— CNN (@CNN) April 22, 2020
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Coronaviruses are a family of viruses that comprise RNA enclosed within an envelope of protein and fat molecules. They commonly infect the respiratory and gastrointestinal tracts of their mammalian and bird hosts.
The coronavirus that causes COVID-19, known as SARS-CoV-2, shares 96% of its genetic sequence with a virus found in bats. This led scientists to conclude that SARS-CoV-2 may have jumped species from bats into humans, possibly via pangolins.
A study in 2017 estimated, bats may play host to more than 3,200 coronaviruses, most of which remain undiscovered. A survey conducted in Myanmar, published in the journal PLOS ONE, has identified six new coronaviruses in bats.
Ecological disruption bringing new viruses into human contact
By bringing people and wild animals into closer contact, ecological disruption, such as clearing forests for agriculture, increases the likelihood that viruses will make the leap into human populations, says Marc Valitutto, who led the study.
“Viral pandemics remind us how closely human health is connected to the health of wildlife and the environment,” says Valitutto, a former wildlife veterinarian who now works for the Global Health Program at the Smithsonian National Zoo and Conservation Biology Institute in Washington, DC.
“Worldwide, humans are interacting with wildlife with increasing frequency, so the more we understand about these viruses in animals — what allows them to mutate and how they spread to other species — the better we can reduce their pandemic potential.”
PREDICT funded by USAID
The project was part of PREDICT, an initiative funded by the U.S. Agency for International Development to discover pathogens with the potential to spread from animals to humans. It brought together scientists from the Smithsonian, the University of California, Davis, and government scientists in Myanmar.
They first identified three sites where humans have come into closer contact with wildlife populations due to changes in land use and development. Two of the sites included cave systems where people have routine exposure to bats through guano harvesting, religious practices, and ecotourism.
Bat Guano and Saliva samples being studied
Between May 2016 and August 2018, the scientists caught bats in mist nets, took saliva samples, then released them. They also collected fresh bat poop (guano) from the floors and entrances of caves.
In the lab, they screened more than 750 bat saliva and fecal samples (Guano) for the RNA sequences of coronaviruses. By comparing these with the sequences of known coronaviruses in a database, they were able to identify the six new coronaviruses.
The authors stress that the newly discovered viruses are not closely related to the coronaviruses that cause SARS, MERS, and COVID-19.
They also don’t know whether the viruses have the potential to cause serious illness in humans.
“Many coronaviruses may not pose a risk to people, but when we identify these diseases early on in animals, at the source, we have a valuable opportunity to investigate the potential threat,” says Suzan Murray, who is director of the Smithsonian’s Global Health Program and a co-author of the study.
“Vigilant surveillance, research, and education are the best tools we have to prevent pandemics before they occur.”
Guano samples accounted for the majority of the coronavirus particles that the researchers found. This suggests that guano may be an important viral transmission route from bats into people and a particular health threat for those who harvest and use it as fertilizer.
Emerging infectious diseases
Human infections that originate in animals are known as zoonoses. Researchers estimate that 60–75% of emerging infectious diseases are zoonoses, and of these, more than 70% may have originated in wildlife species, such as bats.
The authors recommend intensive surveillance of the bat populations that come into close contact with people to identify future health threats.
Online Int’l News with additional input by GVS News Desk